MAX=10**6
prime=[True for i in range(MAX+1)]
prime[0]=prime[1]=False
for i in range(2,MAX+1):
    if not prime[i]:
        continue
    for j in range(2,MAX//i+1):
        prime[i*j]=False
N=int(input())
tmp=0
for i,p in enumerate(prime):
    if p:
        if N%i==0:
            tmp+=1
            while N%i==0:
                N//=i
if N!=1:
    tmp+=1
if tmp<=2:
    print('Yes')
else:
    print('No')