#define _GLIBCXX_DEBUG
#include <bits/stdc++.h>
using namespace std;
#define rep(i, n) for (int i = 0; i < (int)(n); i++)
 
int main() {
    string s;
    cin >> s;
    if (s[0] == '4' | s[0] == '5') cout << "Yes" << endl;
    else cout << "No" << endl;
}