import java.util.*;

public class Main{
  
  public static void main(String[] args){
    
    Scanner sc = new Scanner(System.in);
    
    String s = sc.next();
    
    if(s.charAt(0)=='4' || s.charAt(0)=='5'){
      System.out.println("Yes");
    }else{
      System.out.println("No");
    }
  
  }

}