import java.util.*;

public class Main {
	public static void main(String args[]) {
		Scanner scan = new Scanner(System.in);

		int a = scan.hasNextInt() ? scan.nextInt() : -1;

		if (a > 599 || a < 100) {
			System.out.println("入力エラー1");
			return;
		}

		if (Integer.toString(a).charAt(0) == '4'  || Integer.toString(a).charAt(0) == '5') {
			System.out.println("Yes");
		} else{
			System.out.println("No");
		}

	}
}